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Clinical studies show that patients can experience significant reductions in body weight over several months when the medication is paired with a healthy diet and regular exercise routine

Key Differences Summary# Dosing frequency : MET-097i targets once-monthly dosing (12 injections/year) versus semaglutide's weekly dosing (52 injections/year) or daily oral dosing

Patients who prefer sublingual administration should review our comprehensive guide to oral tirzepatide for detailed protocols and expectations

If constipation worsens during dose escalation, Hamilton recommends talking to your prescribing physician

Prescribers must ensure that thyroid function is optimised and stable before initiating GLP-1 receptor agonist therapy

Lois Donovan, clinical professor at the University of Calgary AB Canada in the Cumming School of Medicine, Department of Medicine, Division of Endocrinology and Metabolism, Department of Obstetrics and Gynecology and lead presenter of the study