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Description

Use: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus Usual Adult Dose for Weight Loss ORAL: Wegovy Tablets: Initial dose (days 1 through 30): 1.5 mg orally once a day Dose escalation: Days 31 through 60: 4 mg orally once a day Days 61 through 90: 9 mg orally once a day SUBCUTANEOUS: Wegovy Injection: Initial dose (weeks 1 through 4): 0.25 mg subcutaneously once a week Dose escalation: Weeks 5 through 8: 0.5 mg subcutaneously once a week Weeks 9 through 12: 1 mg subcutaneously once a week Weeks 13 through 16: 1.7 mg subcutaneously once a week If the 2.4 mg dosage is tolerated for at least 4 weeks and additional weight reduction is clinically indicated: Increase to 7.2 mg subcutaneously once a week

GLP-1s Arent the ProblemBut They Change the Environment Lets be clear: GLP-1 medications are not bad for your pelvic floor

They can offer advice, suggest lifestyle changes, or make adjustments to your treatment plan to help you feel more comfortable

Hypersensitivity reactions: stop using the GLP-1 agonist and get medical help right away if you have any symptoms of a serious allergic reaction including swelling of your face, lips, tongue or throat, severe rash or itching, very rapid heartbeat, problems breathing or swallowing, fainting or feeling dizzy

Subjects receive oral semaglutide 3 mg + placebo, or semaglutide 7 mg + placebo, or semaglutide 14 mg + placebo, or oral sitagliptin 100 mg + placebo [78]