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As people age, stomach acid levels often drop, making it harder to absorb B12 from food
Whilst this paper describes a statistically significant reduction in pain measured by the numeric rating scale (NRS) from baseline in both arms, there was no enhancement of outcome with the addition of B12 and ALA

10.1097/CJI.0000000000000247 84

Mass-spectrometric exploration of proteome structure and function

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