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In a 2017 study published in the Journal of Molecular Medicine , Hsieh and colleagues reported that BPC-157 promoted angiogenesis in chick chorioallantoic membrane and endothelial tube-formation assays and accelerated blood-flow recovery in a rat hindlimb ischemia model, with the effect attributed to activation of the VEGFR2-Akt-eNOS signaling pathway [1]

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Specifically, it is the gliadin component of gluten that is responsible for stimulating the immune-mediated destruction of the intestinal barrier (Smyth 2017)

These dietary components are, therefore, useful in protecting the integrity of the gut barrier and may be effective in limiting the development of gut-associated or extraintestinal inflammatory diseases or could be considered in their treatment

In each case, a provider should confirm a deficiency before starting treatment