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Most people tolerate B12 well, even at high doses, as excess amounts are excreted through urine
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At the 2.5 mg starting dose, a 30 mg vial provides 12 weeks of doses

Treatment Severe thiamine deficiency can possibly kill a goat in 24 hours to a few days if left untreated

NADPH plays a key role in cellular antioxidation systems by providing reducing equivalents to generate reduced forms of antioxidant molecules, which are highly corrected with cancer cell biological behaviors

1999a;39:6973