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These results support the conclusion that simultaneous inhibition of GSH and Trx metabolism pathways induces oxidative stress and clonogenic killing in HNSCCs and this strategy may be useful in sensitizing HNSCCs to EGFR inhibitors.

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The subcutaneous tissue, along with the fat tissue it contains, gives shape to the skin coverings

Drug repurposing is invaluable for detecting novel PD therapeutics