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Acknowledgments Authors express special thanks to Ken Rory and many other colleagues of the Academiacs International network ( accessed on 14 May 2021) for helpful discussions and inspiration
Hanigan for assistance with protocols and the donation of key reagents

The disease is characterised clinically by resting tremor, rigidity and slowness of movement (bradykinesia) with symptoms being partially alleviated by administration of exogenous dopamine (L-dopa)
As of now, the FDA has not approved the use of injectable skin lightening or whitening and continues to crack down on unapproved and deceptively labeled drugs that are currently on the market that mislead consumers into thinking otherwise.

Krppel-like factors (KLFs) are major players in transcriptional networks that control proliferation, apoptosis, differentiation, development, and tumorigenesis
