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Imerslund-Grsbeck syndrome (IGS) is a rare genetic disorder characterized by selective vitamin B12 deficiency co-existing with asymptomatic proteinuria

There are at least 8 isoforms of GPx

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This review systematically synthesizes the immunometabolic regulatory mechanisms of PANoptosis in diabetes and its complications, clarifies its cell-specific roles in -cells, immune cells, and vascular tissues, and evaluates therapeutic strategies targeting the metabolic-immune crosstalk axis and core PANoptotic components, providing new theoretical basis and potential targets for precision intervention in diabetes and its complications.

Vitamin B12 deficiency is a risk every person who has bariatric surgery accepts before going under the knife