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10.1016/j.jaci.2009.12.980 24 ChenC.HaoY.LiangJ.LiuX

318 A study reported that Melatonin inhibits angiogenesis by downregulating the HIF1/ROS/VEGF pathway in HUVECs, 319 while its pro-oxidant activity may also contribute to anticancer effects, highlighting a context-dependent mechanism that warrants further investigation

Plasma was isolated by subsequent centrifugation at 3000 rpm for 10 min at 4 C, then the supernatant was collected

Complementing this, Wu et al., 2019 studied AgNPs of various diameters (3.2, 20.7, 54.7, and 93.6 nm) in B16 mouse melanoma cells and found that nanoparticle size not only affected uptake efficiency but also dictated the endocytic pathways involved

Furthermore, the effective discrimination of AD and non-demented controls based on multiple CpG sites and RNA expression underscores the potential of DNA methylation patterns as biomarkers for AD diagnosis and prognosis (175)