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In addition, GDH inhibition also limits synaptic glutamate uptake (Whitelaw and Robinson 2013), whereas genetic deletion of GDH leads to impaired glutamine metabolism in cultured neurons (Hohnholt et al
Rights and permissions About this article Cite this article Fu, J., Su, X., Li, Z
Probiotic metabolites, such as SCFAs, can enhance NK cell function through epigenetic mechanisms like inhibition of histone deacetylase (HDAC) (112)
doi: 10.1186/s12985-022-01825-y 3 DartoisV
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GDH function in organs Under normal conditions, GDH is a key regulator for amino acid and ammonia metabolism in the human pancreas, liver, and brain
