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Ice for first 48-72 hours, then heat

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You will have paid for an injection that your body did not need

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Second, any mild stimulatory effects from improved cellular energy production are more appropriate during waking hours than before bedtime

after which another etiology of liver disease may be evaluated and the decisions on omaveloxolone reinitiation (i.e., reinitiation at a later time point, reinitiation at reduced dosing, or permanent discontinuation) may be discussed with the patient, taking into consideration other patient characteristics (e.g., age, weight, and disease duration)