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Across randomized clinical trials of GLP-1 drugs involving thousands of participants, the most common side effects are consistently stomach-related including nausea, diarrhea, constipation, and vomiting, he says

Avoid heavy, fatty, or spicy foods

Glucagon increases calorie burning and fat breakdown

[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Holst JJ

You can use the compounded tirzepatide dosage calculator to estimate weight-adjusted exposure

The medication suppresses appetite through GLP-1 and GIP receptor activation , slows gastric emptying , and fundamentally alters the way your brain responds to reward signals