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The following interventions by histamine receptor antagonists and IL-17a antibodies have been shown to reduce the chronic effects of neuroinflammation via targeting components of the MIA pathway to ameliorate social and behavioral difficulties in MIA-exposed offspring: Histamine Receptor Antagonists Histamine plays a significant regulatory role in the immune response as well as in sensory and motor functions, cognition, attention, and social recognition memory [56,57]