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NNMT is a cytosolic enzyme that is primarily expressed in the liver and catalyzes the transfer of methyl group from the cofactor S-(5-adenosyl)-L-methionine (SAM) to other substrates
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(Roberti et al., 2023) reported a novel dual-substrate NNMT inhibitor, CC-410 , which stably binds to and exhibits high specificity in inhibiting NNMT
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