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The mechanisms of action of CoQ10 include restoring ROS imbalances and preventing DNA damage and oocyte apoptosis (Zhang et al., 2019)

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10.1056/NEJMoa1709847 175 RubinB

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In terms of model optimization, biomimetic periodontal flow models or ex vivo periodontal tissue perfusion systems can be established to screen and optimize delivery carriers under conditions that more closely resemble the real clinical environment, thereby narrowing the gap between laboratory research and clinical translation