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Conditions associated with high B12 include liver disease, renal impairment, myeloproliferative disorders, and certain malignancies

An enzyme called NNMT (nicotinamide N-methyltransferase) drains the NAD+ salvage pathway by methylating nicotinamide, one of NAD+'s precursors
Professor Gary Wittert, Adelaide University's chair of medicine, told Fairfax Media this week: ''I wish we had pushed the issue much harder at the time
