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Oxidative stress occurs from normal cellular processes but increasingly from pollution, toxins, stress, and other exposures of modern life

doi: 10.1152/ajpendo.00148.2019 116

Giannetti, A

The IC 50 values for the ripe fruit pulp, ripe fruit seeds, unripe fruit pulp, and unripe fruit seeds were 27.78, 89.1, 77.33, and 75.2 g/mL for HepG2 cells, respectively

Lysosomal cystine levels were regulated by the major facilitator superfamily domain containing 12 (MFSD12)-mediated import and the lysosomal cystine transporter (CTNS)-mediated efflux and were sensed by the AhR-kynurenine pathway [41,42,43]

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