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ROS derived from the Nox subtypes Nox1, Nox2, and Nox4 lead to vascular dysfunction in diabetic retinopathy, and Nox5-derived ROS increase the incidence of abdominal aortic aneurysms in diabetic patients [16, 17]

These pathological processes lead to progressive neuronal loss and subsequent neurological dysfunction

doi: 10.3109/10715769609149066

10.1016/j.freeradbiomed.2011.06.022 89 MaillouxR

The prediction revealed that these cis- acting elements primarily included hormone-related response elements such as auxin, abscisic acid (ABA), salicylic acid (SA), methyl jasmonate (MeJA), and gibberellin acid (GA), stress-related response elements such as light, dehydration, low-temp, and salt stresses, and wound-responsive elements (Fig

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