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Such disruptions in protein function interfere with thyroid hormone biosynthesis and receptor-mediated signaling, resulting in hormonal insufficiency

4c), and this was required for salinazid to extend lifespan (Extended Data Fig

Eine schlechte Verdauung kann Blhungen, einen aufgeblhten Bauch und Verstopfung verursachen und so ein Schweregefhl und einige Zentimeter Bauchumfang mit sich bringen

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Diagnosis needs to be combined with patient history, symptom assessment (Ocular Surface Disease Index), and auxiliary examination [tear film stability: break-up time (BUT) test and tear secretion: Schirmers test] (Schiffman et al., 2000