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Further mechanistic investigations demonstrated that VSEE enhances the amounts of Wnt3a and LRP-5 proteins, thus stabilizing -catenin

Ma F, Wu T, Zhao J, et al

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For example, PRMT1 overexpression is associated with increased arginine methylation and aberrant exon inclusion of SRSF1, which is essential for breast cancer cell growth [47]

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USP2 is lactylated at K447 under TGF1 stimulation and which is required for the activation of USP2-mediated TGF1 We found that the interaction between SIRT2 and USP2, as determined by both endogenous and exogenous co-immunoprecipitation (Co-IP), was present under TGF1 stimulation (Fig