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Moreover, luteolin has been shown to interfere with MAPK/IL-1 signaling and IL-36 release in neutrophilic asthma models, suggesting broader immunomodulatory effects relevant to chronic lung diseases, including fibrosis [143]
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By analyzing the serological indicators of 48 patients with thyroid nodules and 52 healthy people, Li et al
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In addition, elevated methylation of histone H3 lysine 27 (H3K27me3) by EZH2 further stabilizes this reversible quiescent state by repressing lineage-specific gene expression programs (Marso et al., 2022)