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These are not serious and may be minimised with proper use and guidance

Acta Endocrinol (1987) 114(4):497502

22nd June 2026

corroborated by Silverii 2025 RCT meta-analysis (OR 1.55) on a small absolute base

Requires careful sun protection as retinoids increase photosensitivity

doi: 10.1023/A:1015917922980
