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testing should be targeted at individuals with: [15] Symptoms suggestive of deficiency Conditions affecting vitamin D metabolism (chronic kidney disease, malabsorption disorders) Increased fracture risk or metabolic bone disease Deficiency is generally defined as 25(OH)D levels below 25 nmol/L, with insufficiency between 2550 nmol/L

While the exact causes remain complex and not fully understood, it is generally believed that a combination of genetic and environmental factors contributes to its development

Journal of Clinical Medicine 15(2), 740 (2026)

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Why it helps: Protects from light Adds insulation against temperature fluctuations Keeps vials organized with reconstitution dates Label with reconstitution date Essential practice: Write reconstitution date on vial or box immediately after mixing