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Protease-activated receptors 1 and 4 mediate thrombin signaling in endothelial cells

[DOI] [PubMed] [Google Scholar] 212.Teixeira TFS, Collado MC, Ferreira CLLF, Bressan J, Peluzio M do CG
Oral semaglutide may allow shorter intervals (12 hours) since it bypasses first-pass hepatic metabolism differently than injectable formulations

Bibcode:2004Bioc...43.8038B

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Both peptides degrade with repeated freeze-thaw cycles aliquoting into single-use volumes is recommended