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These hypotheses suggest that enhanced ROS production may play a crucial role in mediating synaptic loss and, in turn, causing senile plaques (Uddin et al., 2022) (Figure 3)

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Melatonin Res 2:4466

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Efficacy of N-carbamoyl-L-glutamic acid for the treatment of inherited metabolic disorders

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(Article in Japanese) Moi P, Chan K, Asunis I, et al

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This timeline covers what the clinical and preclinical evidence shows at each stage, what community reports consistently describe, and the factors that determine whether results land on the faster or slower end of the spectrum

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