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Carbidopa is administered with levodopa to inhibit its early conversion to dopamine outside the central nervous system, thereby minimizing side effects like nausea and enhancing the quantity of levodopa penetrating the brain (47)
Resistance to antiangiogenic therapies can be intrinsic, when it is observed at the beginning of the treatment, or acquired, i.e., that it affects the relapsing disease after an initial response to therapy [26,27]
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[DOI] [PubMed] [Google Scholar] 234.Khan R., Anwar F., Ghazali F.M
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