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For example, mitochondria contained in the liver are designed to convert ammonia into a less toxic waste substance known as urea in a series of reactions (7)
GAPDH, which is supposed to prevent accumulation of MG, was also found to be a target of MG modification 18 , highlighting the interaction of oxidative stress and cellular metabolism
Biochim Biophys Acta (2014) 1842(9):157986
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Hepatology 49 , 17181728 (2009)
Transient inhibition of mTOR during manufacture induces metabolic reprogramming and enhances anti-tumor activity of CAR T cells
