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One of only three published human studies on BPC-157, this open-label trial investigated intra-articular injections for knee pain

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10.1016/j.ifset.2021.102645 Innov Food Sci Emerg Technol

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Diabetes Metab J (2022) 46:40213

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John s Wort induces CYP3A4 and can reduce plasma concentrations of PPIs like omeprazole, while curcumin and berberine can inhibit CYP3A4 and P-glycoprotein, raising toxicity risks with drugs such as warfarin, statins, or immunosuppressants

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It has also been linked to behavior like anger and aggression in children

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