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Synthetic antioxidants provide targeted support, while natural oxidants, derived from plant sources, contribute to a holistic and sustainable therapeutic strategy since they are used within regulations parameters (197)

Furthermore, the aggregation of amyloid-beta (A) plaques, which constitute the signature pathologies of AD, have been associated with ferroptosis-linked mechanisms [516]

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Dietary Supplements Potentially Target Plasma Glutathione Levels to Improve Cardiometabolic Health in Patients with Diabetes Mellitus: A Systematic Review of Randomized Clinical Trials

This finding supports the idea that the mutation in pad2-1 close to the glutamate conjugating residues of GSH1 might influence the affinity of the enzyme for BSO, as it was proposed for cad2-1 54,71

Combination of Omega 3 and Coenzyme Q10 exerts neuroprotective potential against Hypercholesterolemia-Induced Alzheimers-Like Disease in rats