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An Insight into Aging, Senescence, and Their Impacts on Wound Healing

The central importance of mitochondria in the overall biology of the cell means that mitochondrial dysfunction can result in or contribute to debilitating diseases, including cancer, diabetes, neurodegenerative conditions and ischemic injuries

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During the development of acute myocardial infarction, elevated Wnt2 promoted -catenin/NF-B signaling by binding to Fzd4 and LRP6, and elevated Wnt4 activated the same signaling by binding to Fzd2 and LRP6, resulting in a pro-fibrotic effect

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J Dairy Sci (2022) 105(2):164960
