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Chronic cortisol elevation increases sebum production, impairs skin barrier function, and amplifies the inflammatory response to clogged pores

Chopyk and Grakoui, 2020), thyroid diseases (Knezevic et al., 2022), celiac disease (Videhult and West, 2016), systemic lupus erythematosus (Opazo et al., 2018

Current analytical methods [130] often lack the sensitivity and specificity to reliably measure internal doses, biodistribution, or the potential for bioaccumulation and biomagnification

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