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Although generally safe, injections should be used with caution in people with a history of allergic reactions to cobalamin or in people with Leber's disease (hereditary optic neuropathy), as B12 may worsen the condition

I noticed i the first few days a slight improvement with entergy and my mood

Happy to discuss this if you want to know more

However, most patients notice relief after just one treatment

Although quite rare, B12 may aid in repairing the myelin sheath depending on the underlying cause of the neuropathy

The conclusion is that B vitamins can be used in treating neuroinflammation and promoting neuroregeneration, potentially serving as an effective therapy for PNI in humans.