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Notably, enhancing lipid utilization or myelin turnover in AD should be approached with caution, as chronic activation of lipid-buffer pathways may gradually compromise myelin integrity and promote demyelination, necessitating stage-specific strategies that balance short-term metabolic support with long-term sheath maintenance

Using Western blotting and real-time PCR, Velho et al

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This model showed high accuracy in estimating the presence of TLS in the kidney, and the receiver operating characteristic curve revealed a high area under the curve value of 0.92 (Figure 6I)