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At that stage, we had no firm animal data to indicate that it could work in a human in the ways that he wanted." (This year Calzada got some clinical results showing AOD's potential to help repair cartilage in animals.) "I said to Steve when he told me, 'If you are going to use it on players, make sure a doctor is involved and make sure it is not banned by WADA'," he recalls

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The 7% body weight reduction observed in mouse models may not translate proportionally to human weight loss it could be more, less, or require entirely different dosing and duration