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(2) ROS also promote the conversion of copper ions into reactive intermediates such as copper peroxyl, hydroperoxyl, and superoxyl radicals [93-95] , which further attack mitochondrial membranes, leading to mitochondrial dysfunction - considered a second hit

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An increase in Egr-1 expression signals cells to grow and repair themselves

(In Russian) [DOI] [PubMed] [Google Scholar] 13.Chen J, Jiang Y, Shi H, Peng Y, Fan X, Li C

Untreated B12 deficiency causes peripheral neuropathy (tingling, numbness, balance issues) and, in severe cases, cognitive decline