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In COPD, airway remodeling is primarily driven by a shift in arginine metabolism toward polyamine synthesis [10]

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There has been significant discussion within the industry and wider stakeholder groups about what evidence, beyond traditional approaches, can be used to support PBAC submissions for listing, and how related uncertainty can be managed

Zhu Z, Luo Y, Lou G, Yihunie K, Wizzard S, DeVilbiss AW, et al