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10.1002/hep.30945 Summary Keywords alcohol, metabolic dysfunction, inflammation, alcohol-related disease, oxidative stress Citation Lee J, Lee J-Y and Kang H (2025) Excessive alcohol consumption: a driver of metabolic dysfunction and inflammation

Yu L, Gao L, Liang B, Zhang L, Wu M, Liu J

They report that a chaperone-dependent E3 ubiquitin ligase, STIP1 homology and U-Box containing protein 1 (STUB1) modulates TFEB content by preferentially ubiquitylating its phosphorylated form as a signal for degradation by the 26S proteasome

(2022) 119:e2200252119

G.PuigjanerJ.CascanteM.LeeW

HIV-infected adults in one study were given 300 mg of alpha-lipoic acid three times daily for six months, which resulted in significant elevations in total glutathione [58]