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Neuronal activity regulates expression of tyrosine hydroxylase in adult mouse substantia nigra pars compacta neurons

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On SD, mutant and wild type were highly sensitive to even small concentrations of H 2 O 2 (Supplementary Figure 2)

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Long-term potentiation (LTP) is one of the main forms of synaptic plasticity, and high-frequency stimulation-induced LTP is dependent on estrogen receptor (ER) activation (Tozzi et al., 2019)

Hemodialysis procedures further amplify oxidative damage via membrane interactions and loss of antioxidants ( FIGURE 4 While oxidative stress represents a fundamental mechanism in red blood cell (RBC) senescence, it is not the exclusive driver of this process