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The most commonly reported adverse effects are the GI symptoms associated with tirzepatide (nausea, reduced appetite) plus the mild headache occasionally seen with AOD 9604

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Switch to a different GLP-1 agonist like semaglutide , which some people tolerate better

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Data from the ALS registry Swabia showed a possible positive association of body mass index (BMI) with ALS decades before the clinical manifestation of ALS 3

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