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Amylin is a pancreatic beta-cell hormone that is typically secreted in combination with insulin in order to manage nutrient intake

50 Though these findings are not directly associated with IC pathogenicity, the data suggest that ICs could limit the effectiveness of therapeutic antibodies in humans

Furthermore, pyocyanin exhibited cytotoxic effects against cancer cell lines such as SK-MEL-30 human melanoma and HT-29 human colon cancer cells, suggesting its potential as a cancer treatment (45)

doi: 10.1016/j.isci.2021.102295 95 KuwataTNishimuraYWhittedSOurmanovIBrownCRDangQet al

Furthermore, it is important to emphasize the regulation of autophagy in CSCs by nanoparticles and their subsequent effects on cancer immunotherapy

Although carnitine has been well tolerated, future studies are needed to evaluate the efficacy of prophylactic carnitine supplementation for the prevention of hepatotoxicity. 12 Some experimental and clinical data suggest that early intravenous supplementation with l-carnitine could improve survival in severe VPA-induced hepatotoxicity