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For instance, SAMe, in a double-blind, placebo-controlled study of 60 AD patients who received a daily dose of 400 mg for 180 days, reported improved cognitive functions (188)

Protein oxidation can also affect enzymes that regulate sperm metabolism, reducing the availability of ATP, which is required for motility and fertilization

[171] reported that APOE*3Leiden.CETP mice exposed to alternating lightdark cycleinduced circadian disruption presented a notable increase in atherosclerosis, with a nearly twofold increase in the size and severity of lesions [171]

The amino acid and nucleotide metabolism is equally influential since the metabolic reprogramming should be regarded as a whole and each part is no way to neglect

doi:10.2147/CIA.S361519

Together, these findings underscore the vulnerability of the developing brain to NPs exposure and highlight the need for preventive strategies to safeguard fetal neurodevelopment during pregnancy