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No clinical trials have evaluated their combined use, and major US guidelines do not recommend lipotropic injections

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Certain patients, such as those with a hereditary eye condition called Lebers disease, should avoid B12 injections altogether, as these may worsen symptoms

Preparing The B12 Injection Site Before administering the injection, it's essential to prepare the injection site properly to minimize the risk of infection and ensure optimal absorption of the B12 solution

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