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This increase in bone density was attributed to a decrease in osteoclast, as well as, inflammatory cytokines in the bone and bone marrow in the germ free mice vs conventionally raised mice [132]

Glutathione: systemic protectant against oxidative and free radical damage

Literature suggests that decreased GSH/GSSG ratios reflect OS (Zitka et al., 2012), due to decreased GSH levels, increased GSSG values, or both

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Increased iron uptake occurs through upregulation of transferrin receptor 1 and divalent metal transporter 1, coupled with impaired iron export and storage due to reduced expression of ferroportin expression and dysfunction ferritin buffering [205, 206]