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J., Croughan, M

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4.6.4 Neuroinflammation Central and systemic inflammation play a role in ALS pathogenesis, with some immune cell targets [8, 233] leading to investigational considerations (Table 4)

AMPK is activated under energy stress conditions such as nutrient deficiency or hypoxia, as well low intracellular ATP with concomitant increase of AMP [41]

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