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Although further dose-optimization studies are warranted to maximize the antiviral effect in the lower respiratory tract, phenformin showed antiviral activity in the upper respiratory tract, the main anatomic site for viral entry and spread

Stimulation of de novo glutathione synthesis by NFT concentrations in this range was observed in HepG2 cells, PHHs, or human neuronal cells, but not to the same extent in other cell types such as human iPSC-derived astrocytes
Studies indicate that soursop exhibits cytotoxic effects on leukemic cancer cells through the induction of apoptosis and the inhibition of proliferation

Royea, J

Designing and engineering Methylorubrum extorquens AM1 for itaconic acid production

Figure 4 summarizes the metabolites affected by these treatments as well as the pathway for these metabolites
