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In addition, the glutathione conjugates 2&4-OHE2-Cys, 2&4-OHE1-SG, and 2&4-OHE2-SG were significantly decreased, whereas 2&4-OHE2(E1)-NAcCys and 2&4-OHE1-Cys levels were unaffected in COC users
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The breadth of gene modulation raises a fundamental question: how does a three-amino-acid peptide influence thousands of genes
As a small tripeptide (~403 Da), GHK-Cu is susceptible to rapid proteolytic degradation in plasma
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