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Collectively, our findings indicate that in AML cells, GPX4 inhibition induces ferroptosis, which is regulated by mitochondrial lipid redox and ETC

Signs of infection are increasing redness, swelling, pain, and fever

Krzystek-KorpackaMKempiskiRBromkeMANeubauerK

However, the basic biological mechanisms leading to these clinical differences are not well-understood

This result is consistent with the changes in xanthine metabolism observed in the statistical and network analyses, although we note that it should not be considered as validation, as the same input data was used for these analyses