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Interestingly, recent studies indicate that lipopolysaccharide-stimulated macrophages also use the GABA shunt to generate succinate, which activates the transcription factor HIF-1 to enhance the production of the cytokine interleukin-1 for innate immunity
doi: 10.1136/adc.65.10.1109
Consistency is key, as visible results typically appear after 46 weeks of regular use
Yu, W.-l, Guizzunti, G., Foley, T
Hope JH
