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Effects of nanotoxicity on female reproductivity and fetal development in animal models

Hepatocyte NLRP3 interacts with PKC to drive hepatic insulin resistance and steatosis

Moreover, an abundance of prior studies have underscored the protective effects of Nrf2/HO-1 pathway activation against renal oxidative damage in diabetic models (61-63)

nevertheless, animal models have indicated reproductive toxicity and development retardation at excessively high doses (Gota et al., 2010)

Heterotrimeric G protein subunit G q is a master switch for G-mediated calcium mobilization by G i -coupled GPCRs

This necrotic pathway, akin to its effects on apoptosis and autophagy, contributes to metformins antitumor efficacy