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This device released a metered dose of insulin into a chamber covering the participants nose, which was then inhaled by breathing regularly for 2 min until the prescribed dose was delivered

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10.1371/journal.pone.0148424 PLoS One 4 BreaD.PoonC.BenakisC.LubitzG.MurphyM.IadecolaC.et al (2021)
Ethics statement The studies involving humans were approved by Ethical Committees of the Instituto de Biologa y Medicina Experimental, Buenos Aires (Ref: CE 001/April 2019)
